Clinical research progress on pediatric lung transplantation
10.3969/j.issn.1674-7445.2022.03.010
- VernacularTitle:儿童肺移植临床研究进展
- Author:
Huixing LI
1
;
Wenjun MAO
Author Information
1. Department of Thoracic Surgery, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi 214023, China
- Publication Type:Research Article
- Keywords:
Pediatric lung transplantation;
Surgical method;
Donation after brain death;
Ex vivo lung perfusion (EVLP);
Lung allocation score;
Extracorporeal membrane oxygenation (ECMO);
Chronic lung allograft dysfunction (CLAD);
Bronchiolitis obliterans syndrome (BOS)
- From:
Organ Transplantation
2022;13(3):344-
- CountryChina
- Language:Chinese
-
Abstract:
Lung transplantation is an efficacious treatment for end-stage lung diseases in children. Shortage of donor lungs, poor donor-recipient matching, difficult postoperative management, multiple postoperative complications and high fatality jointly restrict the development of pediatric lung transplantation. However, significant progress has been achieved in each transplantation center along with the popularization of organ donation after citizen' s death, advancement of medical science and technology and accumulation of lung transplantation experience. In recent years, clinical application of donor lung from donation after brain death and marginal donor lung repair, maturity of perioperative life support technology and surgical transplantation procedure and reference of management experience after adult lung transplantation have accelerated rapid development of pediatric lung transplantation. In this article, current status and progress on primary diseases, utilization and allocation of donor lungs, selection of surgical techniques, management of postoperative complications and clinical prognosis of pediatric lung transplantation were elucidated, aiming to provide reference for clinical diagnosis and treatment.
