Determination of antioxidant activity of Polygoni Multiflori Radix Praeparata by HPLC-DPPH
10.11665/j.issn.1000-5048.20220208
- VernacularTitle:HPLC-DPPH在线联用技术评价制首乌的抗氧化活性
- Author:
Jinzhu QIAN
1
;
Ming LIANG
;
Yi YU
;
Yalei DENG
;
Shijia LIU
;
Huiming PANG
;
Jin QI
Author Information
1. 中国药科大学中药学院
- Publication Type:Journal Article
- Keywords:
Polygoni Multiflori Radix Praeparata;
HPLC-DPPH;
on-line analysis;
antioxidant activity;
quality evaluation
- From:
Journal of China Pharmaceutical University
2022;53(2):185-191
- CountryChina
- Language:Chinese
-
Abstract:
An on-line HPLC-DPPH system was developed to determine the antioxidant activity of 16 batches of Polygoni Multiflori Radix Praeparata. By analyzing the chromatographic and biological activity fingerprints of 16 batches of Polygoni Multiflori Radix Praeparata, the dose-effect relationship was established and the total antioxidant activity was quantified by activity addition.The results suggested that the online HPLC-DPPH method can evaluate the antioxidant activity of different bathches of Polygoni Multiflori Radix Praeparata, with different processing methods, aiming to provide datasupport and scientific basis forquality evaluation of Polygoni Multiflori Radix Praeparata.