Epidemiology and functional outcome of venous thromboembolism after stroke in rehabilitation wards

Xiaoli WU; Xueyan HU; Yuge Zhang; Changqing YE; Yudong Chen; Hanzhi LI; Lingyu Yang; Fei Gao; Yuqi Yang; Lei Shan; Lixu Liu

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Epidemiology and functional outcome of venous thromboembolism after stroke in rehabilitation wards

VernacularTitle:脑卒中康复患者静脉血栓的发病率及对功能的影响
Author: Xiaoli WU ^{1
,

2} ; Xueyan HU ^{1
,

2} ; Yuge ZHANG ^{1
,

2} ; Changqing YE ^{1
,

2} ; Yudong CHEN ^{1
,

2} ; Hanzhi LI ^{1
,

2} ; Lingyu YANG ^{1
,

2} ; Fei GAO ^{1
,

2} ; Yuqi YANG ^{1
,

2} ; Lei SHAN ^{1
,

2} ; Lixu LIU ^{1
,

2}
Author Information

1. 1. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China 2. Beijing Bo'
2. ai Hospital, China Rehabilitation Research Center, Beijing 100068, China
Publication Type:Journal Article
Keywords: stroke, venous thromboembolism, pulmonary embolism, rehabilitation, risk factors
From: Chinese Journal of Rehabilitation Theory and Practice 2022;28(1):44-49
CountryChina
Language:Chinese
Abstract: Objective To explore the risk of venous thromboembolism (VTE), especially lower-extremity deep vein thrombosis (DVT) and pulmonary embolism (PE), for stroke patients in rehabilitating, and the functional outcome. Methods A total of 3 557 stroke patients in the neurological rehabilitation center of Beijing Bo'ai Hospital for stroke rehabilitation from January, 2015 to October, 2020 were reviewed through the electronic medical record system. Demographic characteristics, stroke characteristics (type and location), laboratory data (D-dimer polymer and arterial partial pressure of oxygen), motor function (Brunnstrom stage, Fugl-Meyer Assessment of motor and balance, modified Ashworth Scale score of triceps crus, and Holden Walking Ability Classification), activities of daily living (Barthel Index), and anticoagulant/antiplatelet treatment data were collected and analyzed. Results The incidence of DVT and PE was 28.5% and 1.29%, respectively. Most were found 30 days later after onset. The incidence of PE was higher after ischemic stroke (χ2 = 12.49, P < 0.001) rather than hemorrhagic stroke. The patients with hemispheric stroke, severe lower-extremity paralysis, and poor activities of daily living were more prone to complications associated with VTE. After rehabilitation, the function of stroke patients with PE could be improved (|t| > 4.302, P < 0.001). Conclusion The risk of DVT and PE in patients during stroke convalescence may not be negligible, and those with older age, previous history of thrombosis, severe stroke, and severe limb paralysis may be stratified in high-risk. Following anticoagulation treatment, early individualized comprehensive rehabilitation can be done for patients with PE to improve their function and activities of daily living.