Progress in hydrogel implantation in treatment of heart failure
- VernacularTitle:水凝胶植入在心力衰竭治疗中的研究进展
- Author:
Pengxu KONG
1
;
Xiangbin PAN
1
Author Information
1. Structural Heart Disease Center, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, P. R. China
- Publication Type:Journal Article
- Keywords:
Hydrogel;
heart failure;
treatment;
tissue engineering;
clinical trial;
review
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2022;29(04):502-507
- CountryChina
- Language:Chinese
-
Abstract:
Heart failure affects quality of life and life expectancy of tens of millions of individuals. There are no available economic and effective treatments for end-stage heart failure. Hydrogels are novel tissue engineering materials, which have the potential to ameliorate myocardium remodeling, increase cardiac output, improve quality of life and prolong life span by implantation into myocardium. The preclinical experiments and clinical trials have greatly explored the function of hydrogels in heart failure. In this review, we summarized the approaches of implantation, mechanism and clinical outcomes of the hydrogels.
