Independent risk factors related to acute respiratory distress syndrome after acute type A aortic dissection surgery: A retrospective analysis
- VernacularTitle:急性 A 型主动脉夹层术后发生急性呼吸窘迫综合征相关危险因素分析
- Author:
Cheng AN
1
;
Chengxin ZHANG
1
;
Ziqiang SHUAI
1
;
Can LIU
1
;
Shenglin GE
1
Author Information
1. Department of Cardiovascular Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, P. R. China
- Publication Type:Journal Article
- Keywords:
Stanford type A aortic dissection;
acute respiratory distress syndrome;
oxygenation index;
risk factors
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2022;29(04):473-477
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the independent risk factors associated with postoperative acute respiratory distress syndrome in patients undergoing type A aortic dissection surgery. Methods The clinical data of 147 patients who underwent acute type A aortic dissection surgery in the First Affiliated Hospital of Anhui Medical University from 2015 to 2019 were retrospectively analyzed. There were 110 males at age of 51.9±10.1 years and 37 females at age of 54.3±11.1 years. According to whether the patients developed ARDS after surgery, all of the patients were divided into a ARDS group or a non-ARDS group. Logistic regress analysis was utilized to establish the predictive mode to identify the independent risk factors related to ARDS. Results Of the patients, 25 developed postoperative ARDS. Among them, 5 patients were mild ARDS, 13 patients were moderate, and 7 patients were severe ARDS. Multivariate logistic regression analysis showed that deep hypothermic circulatory arrest time [odds ratio (OR)=1.067, 95% confidence interval (CI) 1.014-1.124, P=0.013], cardiopulmonary bypass time (OR=1.012, 95%CI 1.001-1.022, P=0.027) and perioperative plasma input (OR=1.001, 95%CI 1.000-1.002, P=0.011) were independently associated with ARDS in patients undergoing acute A aortic dissection surgery. Receiver operating characteristic (ROC) curve analysis demonstrated a good discrimination ability of the logistic regression model, with an area under the curve of 0.835 (95%CI 0.740-0.929, P=0.000). Conclusion Duration of deep hypothermic circulatory arrest, cardiopulmonary bypass time and perioperative plasma are independent risk factors for postoperative ARDS in patients undergoing type A aortic dissection surgery.
