Effect of intraoperative ventilation modes on postoperative pulmonary complications after cardiac surgery under cardiopulmonary bypass: A retrospective cohort study
- VernacularTitle:术中通气模式对体外循环下成人心脏手术后肺部并发症影响的回顾性队列研究
- Author:
Wenjie MAO
1
,
2
,
3
;
Rongjuan JIANG
1
,
4
,
5
;
Hong YU
6
;
Mengqiu ZHANG
6
;
Hai YU
6
Author Information
1. 1. Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China
2. 2. Department of Anesthesiology, Jianyang People&rsquo
3. s Hospital, Chengdu, 641400, P. R. China
4. 3. Department of Anesthesiology, Chengdu Second People&rsquo
5. s Hospital, Chengdu, 610017, P. R. China
6. Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China
- Publication Type:Journal Article
- Keywords:
Pressure-controlled ventilation-volume guarantee;
pressure-controlled ventilation;
volume-controlled ventilation;
cardiac surgery;
postoperative pulmonary complications
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2022;29(03):356-365
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the association of intraoperative ventilation modes with postoperative pulmonary complications (PPCs) in adult patients undergoing selective cardiac surgery under cardiopulmonary bypass (CPB). Methods The clinical data of 604 patients who underwent selective cardiac surgical procedures under CPB in the West China Hospital, Sichuan University from June to December 2020 were retrospectively analyzed. There were 293 males and 311 females with an average age of 52.0±13.0 years. The patients were divided into 3 groups according to the ventilation modes, including a pressure-controlled ventilation-volume guarantee (PCV-VG) group (n=201), a pressure-controlled ventilation (PCV) group (n=200) and a volume-controlled ventilation (VCV) group (n=203). The association between intraoperative ventilation modes and PPCs (defined as composite of pneumonia, respiratory failure, atelectasis, pleural effusion and pneumothorax within 7 days after surgery) was analyzed using modified poisson regression. Results The PPCs were found in a total of 246 (40.7%) patients, including 86 (42.8%) in the PCV-VG group, 75 (37.5%) in the PCV group and 85 (41.9%) in the VCV group. In the multivariable analysis, there was no statistical difference in PPCs risk associated with the use of either PCV-VG mode (aRR=0.951, 95%CI 0.749-1.209, P=0.683) or PCV mode (aRR= 0.827, 95%CI 0.645-1.060, P=0.133) compared with VCV mode. Conclusion Among adults receiving selective cardiac surgery, PPCs risk does not differ significantly by using different intraoperative ventilation modes.
