Epidemiological characteristics of 45 year-old or older HIV-infected persons and patients with AIDS in Chengdu
10.3969/j.issn.1006-2483.2022.02.034
- VernacularTitle:成都地区45岁及以上艾滋病病毒感染者和艾滋病患者流行特征分析
- Author:
Yaling NAN
1
;
Lingli ZHAO
1
;
Chunrong ZHAO
1
;
Jiachuan WANG
1
Author Information
1. Department of Infectious Diseases ,The Second Affiliated Hospital of Chengdu Medical College , Nuclear Industry 416 Hospital ,Chengdu , Sichuan 610051 , China
- Publication Type:Journal Article
- Keywords:
Human immunodeficiency virus;
Acquired immune deficiency syndromes;
Epidemiology characteristics
- From:
Journal of Public Health and Preventive Medicine
2022;33(2):149-153
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the epidemiological characteristics of 45 year-old or older human immunodeficiency virus (HIV)-infected persons and patients with acquired immune deficiency syndrome (AIDS) in Chengdu. Methods Epidemiological methods were used to analyze the data of 45 year-old or older patients with HIV/AIDS reported in Chengdu from 2018 to 2020. Results From 2018 to 2020, there were 219 newly reported cases aged 45 and above (35.67%) with HIV/AIDS in Chengdu, and the differences among them were statistically significant (χ2=6.45, P<0.05). Among the subjects, HIV infected cases accounted for 72.60%, males accounted for 75.80%, most subjects were 56 - 65 years old (48.86%), living in Jinjiang District (39.73%), working in service industries (36.99%), divorced or widowed (67.58%), and Han people (72.15%). There were no significant differences in above characteristics of HIV-infected persons and patients with AIDS from 2018 to 2020 (χ2=0.29, 0.22, 5.65, 1.92, 5.68, 1.12, 2.12, 0.39, P>0.05). 75.34% of the patients were infected through heterosexual transmission, and 50.68% were detected at treatment. The proportion of patients whose first CD4 cell test result was lower than 200/μL was relatively higher (43.84%). Nearly 81.28% of the patients received antiviral therapy, and the mortality reached 16.89%. From 2018 to 2020, the difference in transmission route, sample source, the first examination results of CD4 cells, antiviral treatment, or prognosis was not statistically significant (χ2=1.29, 3.59, 1.56, 0.01, 0.35, P>0.05). Fever (62.10%), fatigue (42.01%), and lymph node enlargement (28.77%) were main symptoms of the patients. 51.14% were detected in outpatient examinations, and most patients were accompanied by at least one opportunistic infection. Cytomegalovirus infection (56.16%) and Mycobacterium tuberculosis infection (36.53%) were main virus infection types. From 2018 to 2020, there was no significant difference in symptoms, visiting departments or combined infection (χ2=0.07-3.00, 3.00, 0.20-2.61, P>0.05). Conclusion The prevalence of HIV/AIDS is relatively severe in 45 year-old or older people in Chengdu. The constituent ratio and the incidence rate show an upward trend. Therefore, individualized prevention and control strategies should be formulated for 45 year-old or older people to effectively suppress the transmission of HIV/AIDS in the middle-aged and the elderly.
