Research progress on the mechanism of nutritional intervention in the progression of metabolic-associated fatty liver disease
10.3969/j.issn.1006-2483.2022.02.028
- VernacularTitle:营养干预在代谢相关性脂肪肝疾病进展中的作用机制研究进展
- Author:
Hongxia CHEN
1
,
2
,
3
;
Zhiqiang GAO
2
;
Zhongji MENG
3
;
Liegang LIU
4
Author Information
1. Institute of Biomedicine, Taihe Hospital, Hubei University of Medicine , Shiyan , Hubei 442000 , China
2. School of Public Health and Health Management, Hubei University of Medicine, Shiyan, Hubei 442000 , China
3. Department of Infectious Diseases, the First Clinical College, Hubei University of Medicine , Shiyan , Hubei 442000 , China
4. Department of Nutrition and Food Hygiene, School of Public Health, Tongji Medical College , Huazhong University of Science and Technology , Wuhan , Hubei 430030 , China
- Publication Type:Journal Article
- Keywords:
Metabolic-associated fatty liver disease;
Nutritional intervention;
Progression
- From:
Journal of Public Health and Preventive Medicine
2022;33(2):122-127
- CountryChina
- Language:Chinese
-
Abstract:
Metabolic-associated fatty liver disease (MAFLD) is considered as a multifactorial disease including genetic, physiological, and environmental factors, in which different factors overlap in various pathways, leading to metabolic impairment and liver damage. The main risk factors for MAFLD are overweight/obesity, insulin resistance/type 2 diabetes, hypertriglyceridemia and related dietary behaviors, mainly the intake of fructose beverages. Adherence to the Mediterranean diet is an important predictor of changes in liver fat content in patients with MAFLD. There is increasing evidence that prescribing specific supplements or nutraceuticals that have been proven to have hepatoprotective effects for MAFLD patients can accelerate the improvement of liver enzymes and liver steatosis or might prevent or delay the progression of MAFLD disease.
