Application of adjusted limited dependent variable mixed model in the mapping of pharmacoeconomic health utility scale
- VernacularTitle:调整有限因变量混合模型在药物经济学健康效用量表映射中的运用
- Author:
Chuchuan WAN
1
;
Huaifu XU
1
Author Information
1. School of International Pharmaceutical Business，China Pharmaceutical University，Nanjing 211198，China
- Publication Type:Journal Article
- Keywords:
adjusted limited dependent variable mixed model;
health utility value;
mapping;
EuroQoL group ’s 5D
- From:
China Pharmacy
2022;33(7):867-872
- CountryChina
- Language:Chinese
-
Abstract:
OBJ ECTIVE To introduce adjusted limited dependent variable mixed model （ALDVMM）and study its application in mapping research ，so as to provide reference for pharmacoeconomic evaluation that needs to obtain health utility value through mapping. METHODS Using the method of literature research ，ALDVMM was introduced from the aspects of development background，model principle ，model determination and test ，model advantages and the current application of the model in empirical research. RESULTS & CONCLUSIONS ALDVMM is a mixed model developed by foreign scholars for the truncation and multimodality phenomenon of EuroQoL group ’s 5D（EQ-5D）at the health utility value 1. Compared with the traditional model，ALDVMM is feasible and has more advantages ，and can more effectively and flexibly capture the actual distribution of EQ-5D and deal with the boundary value problem ，which is helpful to obtain the health utility value more accurately and efficiently and carry out high-quality pharmacoeconomic evaluation.
