Effects of sunlike spectrum LED illumination on retinal blood perfusion in children and adolescents: a randomized controlled trial
10.16835/j.cnki.1000-9817.2022.03.005
- VernacularTitle:类太阳光谱LED照明对儿童青少年视网膜血流灌注影响的随机对照临床试验
- Author:
CHEN Jun，CHEN Yousan，WANG Jingjing, YANG Jinliuxing，XIE Hui，DU Linlin，ZHANG Bo，WU Xiaoyan，HE Xiangui，XU Jianxing
1
Author Information
1. Shanghai Eye Disease Prevention and Treatment Center/Shanghai Eye Hospital/Shanghai Vision Health Center (Shanghai Children Myopia Institute), Shanghai (200050) , China
- Publication Type:期刊文章
- Keywords:
Retina;
Light;
Randomized controlled trial;
Regression analysis;
Child;
Adolescent
- From:
Chinese Journal of School Health
2022;43(3):338-340
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the effect of sunlike spectrum LED illumination on retinal blood flow perfusion, and to explore the the correlation between sunlike spectrum LED illumination and eye health indicators in children and adolescents.
Methods:A randomized control double blind trial was conducted. The ordinary LED table lamp in the control group(11) and the sunlike spectrum LED table lamp in the experimental group(12) had a fitting degree of 87% and 95% with the daylighting spectrum, respectively. Two sample independent t test and multivariable linear regression model were applied to compare the changes of retinal blood perfusion before and after the trial.
Results:After near reading for 1 hour, the retinal capillary density in the superficial and deep layers of the subjects in the ordinary LED illumination group decreased (superficial layer: -3.05±2.04 , P <0.01; deep layer: -4.03± 4.94, P =0.02), no significant decrease was found in the sunlike spectrum LED illumination group (superficial layer: -0.59± 1.44, P =0.18; deep layer: -0.49±4.27, P =0.70). Multivariable regression analysis found that compared with ordinary LED illumination, sunlike spectrum LED illumination could significantly alleviate the decrease in capillary density in the superficial and deep retinal layers, respectively ( β =2.83, 95% CI =1.54-4.12, P <0.01; β =4.21,95% CI =0.58-7.84, P =0.02).
Conclusion:Sunlike spectrum LED illumination can alleviate the decrease in retinal blood perfusion caused by near work among children and adolescents, suggesting that it may delay the onset and development of myopia. Prevention and control of myopia needs to pay attention to the spectral power distribution of artificial illumination.
