The Relationship between Brachial Ankle Pulse Wave Velocity andAtherosclerotic Risk Factors.
- Author:
Sung Woo KIM
1
;
Kyu Hong KIM
;
Seong Youn HWANG
;
Seung Ho CHOI
;
Sunjung LEE
;
Young Cheol CHOI
;
Si Youl JUN
;
Jong Kwon PARK
Author Information
1. Department of Surgery, Masan Samsung Hospital,Sungkyunkwan University School of Medicine, Masan, Korea. jongkwon.park@gmail.com
- Publication Type:Original Article
- Keywords:
Pulse;
Wave;
Velocity;
Atherosclerotic risk factor
- MeSH:
Aging;
Animals;
Ankle;
Arm;
Body Weight;
Cholesterol;
Cholesterol, LDL;
Delivery of Health Care;
Glycosaminoglycans;
Humans;
Hypertension;
Male;
Ohio;
Pulse Wave Analysis;
Risk Factors;
Smoke;
Smoking;
Vascular Stiffness
- From:Journal of the Korean Society for Vascular Surgery
2008;24(1):6-10
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Aging and atherosclerotic changes enhance the stiffness of the arterial wall, and the pulse wave travels faster in stiffer vessel. Measurement of the brachial ankle pulse wave velocity (baPWV) is a non-invasive method for evaluating the stiffness of the vessel wall. We investigated the relation between the baPWV and risk factors for atherosclerosis. METHOD: We studied 180 subjects (38 male and 142 female; mean age 46 years, range 24 to 76 years). The instrument used for evaluating the baPWV was a Vasoguard (VIASYS Healthcare, Dublin, Ohio, USA), and measurements were performed in the right arm and in both ankles. Data were analyzed using Pearson correlation, t-test, and multiple regression analysis. Multiple regression analysis was performed for age, sex, smoking, hypertension, height, weight, body mass index (BMI), total cholesterol, LDL, HDL, TG, and HbA1c. RESULT: Right and left baPWVs were significantly increased (P<0.05) in subjects with the following risks: older age, high body weight, high BMI, high total cholesterol, high LDL, high TG, high HbA1c, and low HDL. Right and left baPWVs were also significantly increased (P<0.05) in male subjects with a history of smoking and hypertension. Multiple regression analysis showed that age, sex, and LDL were independent determinants of the right and left baPWVs. CONCLUSION: This study provides evidence that increased age, male gender, and high serum LDL levels are risk factors that contribute to arterial stiffness. Measurement of the baPWV may be a useful method for evaluating vascular status.
