Childhood Asymmetry Labium Majus Enlargement.
10.4132/KoreanJPathol.2011.45.5.529
- Author:
Mi Jin GU
1
;
Sang Yoon KIM
Author Information
1. Department of Pathology, Daegu Fatima Hospital, Daegu, Korea. gmjap@fatima.or.kr
- Publication Type:Case Report
- Keywords:
Child;
Vulva;
Hypertrophy;
Enlargement;
Puberty
- MeSH:
Child;
Fibroma;
Hamartoma;
Humans;
Hyperplasia;
Hypertrophy;
Lipoma;
Puberty;
Vulva
- From:Korean Journal of Pathology
2011;45(5):529-531
- CountryRepublic of Korea
- Language:English
-
Abstract:
Childhood asymmetry labium majus enlargement (CALME) is a disctinctive clinicopathologic entity of pre- and early puberty first described in 2005. It is defined as an expansion of normal soft tissues of the vulva. Although CALME is not a rare lesion, it has been called lipoma, fibroma, hamartoma, and fibrous hyperplasia. CALME is not a true neoplasm and is a physiologic growth in response to hormone. It may tend to resolve spontaneously and recur after surgical resection. We report four cases of CALME with a review of the literature. To the best of the knowledge, this is the first Korean report.
