Pathological staging systems of primary biliary cholangitis
10.3969/j.issn.1001-5256.2022.03.033
- VernacularTitle:原发性胆汁性胆管炎的病理学分期系统
- Author:
Xinhang SONG
1
;
Juanhan YU
2
;
Zhaoping CHENG
3
;
Chen SHAO
4
;
Baocheng DENG
1
Author Information
1. Department of Infectious Diseases, The First Affiliated Hospital of China Medical University, Shenyang 110000, China
2. Department of Pathology, School of Basic Medical Sciences, China Medical University, Shenyang 110000, China
3. Department of Pathology, Ankang Central Hospital, Ankang, Shaanxi 725000, China
4. Department of Pathology, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China
- Publication Type:Reviews
- Keywords:
Primary Biliary Cholangitis;
Pathology;
Stage
- From:
Journal of Clinical Hepatology
2022;38(3):653-655
- CountryChina
- Language:Chinese
-
Abstract:
Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease accompanied by cholestasis, with the histological feature of non-purulent cholangitis. This article briefly describes the advantages and limitations of the traditional pathological staging systems such as Rubin stage, Scheuer stage, and Ludwig stage and the latest Nakanuma stage. Among them, Nakanuma stage refines the histological grading and staging standards to reduce the chance of missed diagnosis due to sampling errors, thus providing more adequate diagnostic and prognostic information for the clinic. A combination of new and traditional staging systems can provide guidance to the diagnosis, treatment, and research of PBC.
