A Curious Case of Diffuse Systemic Sclerosis with Discoid Lupus Erythematosus-Like Lesions: Enigma of an Overlap
- Author:
Belgaumkar Vasudha Abhijit
1
;
Chavan Ravindranath Brahmadeo
1
;
Deshmukh Nitika Sanjay
1
;
Raut Vijay
1
;
Agrawal Kopal
1
Author Information
1. Department of Skin and Venereal Diseases, Byramjee Jeejeebhoy Government Medical College (BJGMC) and Sassoon General Hospital, Pune, Maharashtra, India.
- Publication Type:Case Reports
- Keywords:
Systemic sclerosis;
discoid lupus rrythematosus;
antinuclear antibodies
- From:Malaysian Journal of Dermatology
2020;44(1):50-53
- CountryMalaysia
- Language:English
-
Abstract:
Overlap syndrome is a term used to describe a condition wherein a patient has features of more
than one classic inflammatory rheumatic disease like systemic lupus erythematosus, polymyositis,
scleroderma and rheumatoid arthritis. Individuals with an overlap syndrome may, but need not meet,
complete diagnostic criteria for one or more than one classic rheumatic disease. Mixed connective
tissue disease is a specific subset of overlap syndrome wherein patients have antibodies to the U1
small nuclear ribonuclear protein (anti- U1RNP) and clinical features like hand edema, synovitis,
Raynaud phenomenon, acrosclerosis and biologically or histologically proven myositis. We came
across an interesting case showing clinical features of both Systemic Sclerosis and Discoid Lupus
erythematosus (DLE). On complete evaluation, a final diagnosis of Diffuse Systemic Sclerosis - DLE
overlap was made on the basis of histopathopathological and serological findings. Patient was started
accordingly on systemic and topical medications and responded well.
- Full text:Case Report 3_pg50 (1).pdf
