C-reactive protein (CRP) and Erythrocyte Sedimentation Rate (ESR) Trends following Total Hip and Knee Arthroplasties in an Indian Population – A Prospective Study
https://doi.org/10.5704/MOJ.2107.021
- Author:
Krishna A
1
;
Garg S
2
;
Gupta S
3
;
Bansal H
1
Author Information
1. Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India
2. Department of Orthopaedics, Government Medical College and Hospital, Chandigarh, India
3. Department of Orthopaedics, Fortis Hospital Mohali, Chandigarh, India
- Publication Type:Journal Article
- Keywords:
ESR, CRP, total hip arthroplasty, total knee arthroplasty, Indian population
- From:Malaysian Orthopaedic Journal
2021;15(No.2):143-150
- CountryMalaysia
- Language:English
-
Abstract:
Introduction: To evaluate the trends of C-reactive protein
(CRP) and Erythrocyte sedimentation rate (ESR) in the first
three weeks after uncomplicated total hip (THR) and total
knee (TKR) arthroplasty/replacement in the Indian
population and to compare it with available literature.
Material and methods: A total of 90 patients were enrolled
for this prospective study, of which 30 were unilateral THR,
30 were unilateral TKR (U/L TKR) and 30 were
simultaneous bilateral TKR (B/L TKR). Serum CRP and
ESR were measured on the day before surgery and postoperatively on day 1st, 2nd, 3rd, 7th, 12th, and at the end of
3rd week.
Results: CRP showed a peak at day 2nd with normalisation
to pre-operative value by the end of 3rd week. While ESR
showed a peak on day 3rd and continued to remain elevated
even at end of 3rd week post-operatively. Both mean CRP
and ESR values were higher in THR patients followed by in
B/L TKR and then in U/L TKR patients.
Conclusion: CRP persists to be the best acute phase reactant
in the early post-operative phase with a relatively typical
pattern as compared to ESR. CRP values peak at postoperative day 2nd and then show a gradual decline.
However, its normalisation to pre-operative baseline values
may vary among different groups of population.
- Full text:16.2021my1187.pdf
