Preparing anti-SARS-CoV-2 agent EIDD-2801 by a practical and scalable approach, and quick evaluation
- Author:
Zhen QIN
1
;
Bin DONG
2
;
Renbing WANG
1
;
Dechun HUANG
2
;
Jubo WANG
1
;
Xi FENG
1
;
Jinlei BIAN
1
;
Zhiyu LI
1
Author Information
- Publication Type:Journal Article
- Keywords: Antiviral drug; Decision tree; EIDD-2801; SARS-CoV-2; Shapley value
- From: Acta Pharmaceutica Sinica B 2021;11(11):3678-3682
- CountryChina
- Language:English
- Abstract: EIDD-2801 is an orally bioavailable prodrug, which will be applied for emergency use authorization from the U.S. Food and Drug Administration for the treatment of COVID-19. To investigate the optimal parameters, EIDD-2801 was optimized