Traditional Chinese medicine in COVID-19.
10.1016/j.apsb.2021.09.008
- Author:
Ming LYU
1
;
Guanwei FAN
2
;
Guangxu XIAO
1
;
Taiyi WANG
3
;
Dong XU
1
;
Jie GAO
4
;
Shaoqin GE
4
;
Qingling LI
5
;
Yuling MA
3
;
Han ZHANG
1
;
Jigang WANG
6
;
Yuanlu CUI
1
;
Junhua ZHANG
1
;
Yan ZHU
1
;
Boli ZHANG
1
Author Information
1. State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
2. National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
3. Oxford Chinese Medicine Research Centre, University of Oxford, Oxford OX1 3PT, UK.
4. College of Traditional Chinese Medicine, Hebei University, Baoding 071002, China.
5. Institute of Basic Medicine and Cancer, the Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Chinese Academy of Sciences, Hangzhou 310022, China.
6. Artemisinin Research Center, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
- Publication Type:Review
- Keywords:
COVID-19;
Clinical evidence;
Cytokine storm;
Multiple organ dysfunction;
Potential mechanism;
SARS-CoV-2;
Traditional Chinese medicine;
Viral infection
- From:
Acta Pharmaceutica Sinica B
2021;11(11):3337-3363
- CountryChina
- Language:English
-
Abstract:
COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread across the globe, posing an enormous threat to public health and safety. Traditional Chinese medicine (TCM), in combination with Western medicine (WM), has made important and lasting contributions in the battle against COVID-19. In this review, updated clinical effects and potential mechanisms of TCM, presented in newly recognized three distinct phases of the disease, are summarized and discussed. By integrating the available clinical and preclinical evidence, the efficacies and underlying mechanisms of TCM on COVID-19, including the highly recommended three Chinese patent medicines and three Chinese medicine formulas, are described in a panorama. We hope that this comprehensive review not only provides a reference for health care professionals and the public to recognize the significant contributions of TCM for COVID-19, but also serves as an evidence-based in-depth summary and analysis to facilitate understanding the true scientific value of TCM.
