"Mysterious veil" between the blood group system and pathogens.
10.11817/j.issn.1672-7347.2021.200659
- Author:
Chun OU
1
;
Ying TIAN
2
;
Keying LIANG
3
;
Jun HE
4
Author Information
1. Department of Blood Transfusion, Affiliated Nanhua Hospital, Hengyang Medical School, University of South China, Hengyang Hunan 421001. 1336934623@qq.com.
2. Department of Clinical Research, Affiliated Nanhua Hospital, Hengyang Medical School, University of South China, Hengyang Hunan 421001, China.
3. Department of Blood Transfusion, Affiliated Nanhua Hospital, Hengyang Medical School, University of South China, Hengyang Hunan 421001.
4. Department of Blood Transfusion, Affiliated Nanhua Hospital, Hengyang Medical School, University of South China, Hengyang Hunan 421001. junhe2008@163.com.
- Publication Type:Journal Article
- Keywords:
bacteria;
blood group system;
parasites;
susceptibility;
virus
- MeSH:
Blood Group Antigens/genetics*;
Disease Susceptibility;
Humans
- From:
Journal of Central South University(Medical Sciences)
2021;46(10):1159-1166
- CountryChina
- Language:English
-
Abstract:
As a stable genetic marker of human, blood group is expressed in a polymorphic system in the population. Blood group and pathogens mainly produce effects through the interaction between antigens and antibodies. On the one hand, they can promote pathogen colonization, invasion or evasion of host clearance mechanism, and on the other hand, they can make some hosts less susceptible to corresponding pathogens. By exploring the molecular mechanism between the blood group system and pathogenic microorganisms, it can provide a scientific basis for the treatment of human related diseases and the development of vaccines.
