EEG-controlled functional electrical stimulation rehabilitation for chronic stroke: system design and clinical application.
10.1007/s11684-020-0794-5
- Author:
Long CHEN
1
;
Bin GU
1
;
Zhongpeng WANG
1
;
Lei ZHANG
2
;
Minpeng XU
1
;
Shuang LIU
2
;
Feng HE
1
;
Dong MING
3
Author Information
1. Neural Engineering & Rehabilitation Laboratory, Department of Biomedical Engineering, College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin, 300072, China.
2. Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, 300072, China.
3. Neural Engineering & Rehabilitation Laboratory, Department of Biomedical Engineering, College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin, 300072, China. richardming@tju.edu.cn.
- Publication Type:Randomized Controlled Trial
- Keywords:
brain-computer interface;
chronic stroke;
electroencephalogram;
functional electrical stimulation;
laterality coefficient
- MeSH:
Electric Stimulation;
Electric Stimulation Therapy;
Electroencephalography;
Humans;
Recovery of Function;
Stroke/therapy*;
Stroke Rehabilitation
- From:
Frontiers of Medicine
2021;15(5):740-749
- CountryChina
- Language:English
-
Abstract:
Stroke is one of the most serious diseases that threaten human life and health. It is a major cause of death and disability in the clinic. New strategies for motor rehabilitation after stroke are undergoing exploration. We aimed to develop a novel artificial neural rehabilitation system, which integrates brain-computer interface (BCI) and functional electrical stimulation (FES) technologies, for limb motor function recovery after stroke. We conducted clinical trials (including controlled trials) in 32 patients with chronic stroke. Patients were randomly divided into the BCI-FES group and the neuromuscular electrical stimulation (NMES) group. The changes in outcome measures during intervention were compared between groups, and the trends of ERD values based on EEG were analyzed for BCI-FES group. Results showed that the increase in Fugl Meyer Assessment of the Upper Extremity (FMA-UE) and Kendall Manual Muscle Testing (Kendall MMT) scores of the BCI-FES group was significantly higher than that in the sham group, which indicated the practicality and superiority of the BCI-FES system in clinical practice. The change in the laterality coefficient (LC) values based on μ-ERD (ΔLC
