METTL9 mediated N1-histidine methylation of zinc transporters is required for tumor growth.

Mengyue LV; Dan Cao; Liwen Zhang; Chi HU; Shukai LI; Panrui Zhang; Lianbang Zhu; Xiao YI; Chaoliang LI; Alin Yang; Zhentao Yang; Yi Zhu; Kaiguang Zhang; Wen Pan

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METTL9 mediated N1-histidine methylation of zinc transporters is required for tumor growth.

Author: Mengyue LV ¹ ; Dan CAO ² ; Liwen ZHANG ³ ; Chi HU ³ ; Shukai LI ³ ; Panrui ZHANG ³ ; Lianbang ZHU ¹ ; Xiao YI ⁴ ; Chaoliang LI ³ ; Alin YANG ³ ; Zhentao YANG ³ ; Yi ZHU ⁴ ; Kaiguang ZHANG ¹ ; Wen PAN ⁵
Author Information

1. Department of Gastroenterology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230026, China.
2. Department of Gastroenterology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230026, China. dancao@ustc.edu.cn.
3. Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230026, China.
4. Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, 310024, China.
5. Department of Gastroenterology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230026, China. wenpan@ustc.edu.cn.
Publication Type:Review
MeSH: Animals; Carrier Proteins/metabolism*; Histidine/metabolism*; Humans; Methylation; Methyltransferases/metabolism*; Neoplasm Proteins/metabolism*; Neoplasms/metabolism*; Protein Processing, Post-Translational
From: Protein & Cell 2021;12(12):965-970
CountryChina
Language:English