Molecular deconvolution of the neutralizing antibodies induced by an inactivated SARS-CoV-2 virus vaccine.

Xingdong Zhou; Hui Wang; Qun JI; Mingjuan DU; Yuexia Liang; Huanhuan LI; Fan LI; Hang Shang; Xiujuan Zhu; Wei Wang; Lichun Jiang; Alexey V Stepanov; Tianyu MA; Nanxin Gong; Xiaodong Jia; Alexander G Gabibov; Zhiyong Lou; Yinying LU; Yu Guo; Hongkai Zhang; Xiaoming Yang

Return

Molecular deconvolution of the neutralizing antibodies induced by an inactivated SARS-CoV-2 virus vaccine.

Author: Xingdong ZHOU ¹ ; Hui WANG ² ; Qun JI ³ ; Mingjuan DU ³ ; Yuexia LIANG ¹ ; Huanhuan LI ¹ ; Fan LI ¹ ; Hang SHANG ¹ ; Xiujuan ZHU ² ; Wei WANG ³ ; Lichun JIANG ³ ; Alexey V STEPANOV ⁴ ; Tianyu MA ¹ ; Nanxin GONG ¹ ; Xiaodong JIA ⁵ ; Alexander G GABIBOV ⁴ ; Zhiyong LOU ⁶ ; Yinying LU ⁷ ; Yu GUO ⁸ ; Hongkai ZHANG ⁹ ; Xiaoming YANG ¹⁰
Author Information

1. State Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, 300071, China.
2. Beijing Institute of Biological Products Company Limited, Beijing, 100176, China.
3. Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, 201210, China.
4. M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow, Russia, 117997.
5. Comprehensive Liver Cancer Center, The 5th Medical Center of PLA General Hospital, Beijing, 100039, China.
6. MOE Key Laboratory of Protein Science & Collaborative Innovation Center of Biotherapy, School of Medicine, Tsinghua University, Beijing, 100084, China. louzy@mail.tsinghua.edu.cn.
7. Comprehensive Liver Cancer Center, The 5th Medical Center of PLA General Hospital, Beijing, 100039, China. Luyinying1973@163.com.
8. State Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, 300071, China. guoyu@nankai.edu.cn.
9. State Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, 300071, China. hongkai@nankai.edu.cn.
10. Beijing Institute of Biological Products Company Limited, Beijing, 100176, China. yangxiaoming@sinopharm.com.
Publication Type:Research Support, Non-U.S. Gov't
MeSH: Antibodies, Neutralizing/immunology*; Antibodies, Viral/immunology*; COVID-19/virology*; COVID-19 Vaccines/immunology*; Humans; SARS-CoV-2/pathogenicity*; Spike Glycoprotein, Coronavirus/immunology*; Vaccines, Inactivated/immunology*
From: Protein & Cell 2021;12(10):818-823
CountryChina
Language:English