Effect of glucose metabolism disorders on the short-term prognosis in neonates with asphyxia: a multicenter study in Hubei Province, China.
- Author:
Chun-Hua LIU
1
;
Hui WANG
;
Si-Cong PENG
;
Wen-Xiang WANG
;
Rong JIAO
;
Sha PAN
;
Tian-Jiao ZHU
;
Xiao-Ying LUAN
;
Xiao-Fang ZHU
;
Su-Ying WU
;
De-Guo WEI
;
Bing-Feng FU
;
Rui-Hong YAN
;
Shu-Jie YANG
;
Ya-Hui LUO
;
Gui-Ping LI
;
Min YANG
;
De-Zhao JIA
;
Chuang GAO
;
Xiong-Fei XIAO
;
Li XIONG
;
Jie SUN
;
Jia-Peng XIAO
;
Bo-Wen LI
;
Yan-Ni LI
;
Lian-Hong ZHANG
;
Tian-Guo LI
;
Min CHENG
;
Jian-Xin XIA
;
Shi-Wen XIA
Author Information
- Publication Type:Multicenter Study
- Keywords: Asphyxia; Hyperglycemia; Neonate; Prognosis
- MeSH: Asphyxia; Asphyxia Neonatorum/epidemiology*; Humans; Hyperglycemia; Infant, Newborn; Prognosis; Retrospective Studies
- From: Chinese Journal of Contemporary Pediatrics 2021;23(12):1208-1213
- CountryChina
- Language:English
-
Abstract:
OBJECTIVES:To study the effect of glucose metabolism disorders on the short-term prognosis in neonates with asphyxia.
METHODS:A retrospective analysis was performed on the medical data of the neonates with asphyxia who were admitted to 52 hospitals in Hubei Province of China from January to December, 2018 and had blood glucose data within 12 hours after birth. Their blood glucose data at 1, 2, 6, and 12 hours after birth (with an allowable time error of 0.5 hour) were recorded. According to the presence or absence of brain injury and/or death during hospitalization, the neonates were divided into a poor prognosis group with 693 neonates and a good prognosis group with 779 neonates. The two groups were compared in the incidence of glucose metabolism disorders within 12 hours after birth and short-term prognosis.
RESULTS:Compared with the good prognosis group, the poor prognosis group had a significantly higher proportion of neonates from secondary hospitals (48.5% vs 42.6%,
CONCLUSIONS:Recurrent hyperglycemia in neonates with asphyxia may suggest poor short-term prognosis, and it is necessary to strengthen the early monitoring and management of the nervous system in such neonates.
