Consistency between nasopharyngeal aspirates and bronchoalveolar lavage fluid in pathogen detection in children with pneumonia: an analysis of 533 cases.
10.7499/j.issn.1008-8830.2108154
- Author:
Yong-Han LUO
1
;
Ji-Hong DAI
1
;
Gang GENG
1
;
Wen-Long FU
1
;
Qu-Bei LI
1
;
Chang SHU
1
Author Information
1. Department of Respiratory Diseases, Children's Hospital of Chongqing Medical University/Ministry of Education Key Laboratory of Child Development and Disorders/National Clinical Research Center for Child Health and Disorders/China International Science and Technology Cooperation Base of Child Development and Critical Disorders/Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China com).
- Publication Type:Journal Article
- Keywords:
Bronchoalveolar lavage fluid;
Child;
Consistency analysis;
Nasopharyngeal aspirate;
Pathogen;
Pneumonia
- MeSH:
Bronchoalveolar Lavage Fluid;
Child;
Humans;
Mycoplasma pneumoniae;
Pneumonia;
Pneumonia, Mycoplasma;
Respiratory Tract Infections;
Retrospective Studies
- From:
Chinese Journal of Contemporary Pediatrics
2021;23(11):1127-1131
- CountryChina
- Language:English
-
Abstract:
OBJECTIVES:To study the consistency between nasopharyngeal aspirates (NPA) and bronchoalveolar lavage fluid (BALF) in pathogen detection in children with pneumonia
METHODS:A retrospective analysis was performed on the data of pathogens detected in 533 children with pneumonia from February 2017 to March 2020. The paired McNemar's test was used to compare the difference in pathogen detection between NPA and BALF groups. The
RESULTS:NPA had a sensitivity of 28%, a specificity of 74%, a positive predictive value of 14%, and a negative predictive value of 91% in detecting bacteria, and a
CONCLUSIONS:There is poor consistency between NPA and BALF in the detection of bacteria and viruses, and clinicians should be cautious in diagnosing lower respiratory tract infection based on bacteria or viruses detected in NPA. There is moderate consistency between NPA and BALF in the detection of
