Safety and efficacy of dexmedetomidine hydrochloride combined with midazolam in fiberoptic bronchoscopy in children: a prospective randomized controlled study.
10.7499/j.issn.1008-8830.2107075
- Author:
Jin ZHANG
1
;
Jie-Bo LIU
1
;
Fen-Na ZENG
1
;
Qiao REN
1
;
Hui-Ling LIN
1
;
Li-Li JIAN
1
;
Guo-Le LIU
1
Author Information
1. Department of Pediatrics, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong 518000, China (Liu J-B, Email: jieboliu@hotmail.com).
- Publication Type:Randomized Controlled Trial
- Keywords:
Child;
Dexmedetomidine hydrochloride;
Fiberoptic bronchoscopy;
Midazolam
- MeSH:
Bronchi;
Bronchoscopy;
Child;
Dexmedetomidine/adverse effects*;
Humans;
Hypnotics and Sedatives/adverse effects*;
Midazolam;
Prospective Studies
- From:
Chinese Journal of Contemporary Pediatrics
2021;23(10):981-986
- CountryChina
- Language:English
-
Abstract:
OBJECTIVES:To study the safety and efficacy of dexmedetomidine hydrochloride combined with midazolam in fiberoptic bronchoscopy in children.
METHODS:A total of 118 children who planned to undergo fiberoptic bronchoscopy from September 2018 to February 2021 were enrolled. They were divided into a control group (
RESULTS:Compared with the control group, the observation group had significantly decreased MAP at T
CONCLUSIONS:Dexmedetomidine hydrochloride combined with midazolam is a safe and effective way to administer general anesthesia for fiberoptic bronchoscopy in children, which can ensure stable vital signs during examination, reduce intraoperative adverse reactions and postoperative agitation, shorten examination time, and increase amnesic effect.
