Effects of Microbial Communication on The Growth of Periodontopathogens.
- Author:
Chung Koo LEE
1
;
Dong Heon BAEK
Author Information
1. Department of Oral Microbiology and Immunology, College of Dentistry, Dankook University, Anseo-Dong, Dongnam-Gu, Cheonan, Choongnam, 330-714, Korea. micro94@gmail.com
- Publication Type:Original Article
- Keywords:
biofilm;
periodontopathogens;
early colonizer;
late colonizer
- MeSH:
Bacteria;
Biofilms;
Coculture Techniques;
Colon;
Forsythia;
Fusobacterium nucleatum;
Porphyromonas gingivalis;
Proteins;
Streptococcus gordonii;
Tooth;
Treponema denticola
- From:International Journal of Oral Biology
2010;35(4):197-202
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Most oral microorganisms exist as biofilms which initiate formation via the attachment of an early colonizer to host proteins on the tooth surface. Fusobacterium nucleatum act as a bridge between early and late colonizers. Dental biofilms eventually comprise dental pathogens such as Porphyromonas gingivalis, Treponema denticola and Tannerella forsythia. To evaluate the effects of mutual interactions between oral bacteria on the growth of biofilms, periodontopathogens were co-cultured with a 0.4 microm barrier. Streptococcus gordonii inhibited the growth of F. nucleatum and periodontopathogens. However, F. nucleatum, P. gingivalis and T. denticola activated the growth of other bacteria. A co-culture system of early and late colonizers could be a useful tool to further understand bacterial interactions during the development of dental biofilm.