Toxic Effects of Long-term Exposure to PM
10.19746/j.cnki.issn.1009-2137.2021.05.016
- Author:
Yong-Zhong HE
1
;
Li-Li LIU
1
;
Chuan TIAN
1
;
Xiao-Huan MO
1
;
Zhong-Lyu YE
2
Author Information
1. Children's Medical Center, The Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, Guangdong Province, China.
2. Children's Medical Center, The Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, Guangdong Province, China,E-mail:lzy8151@126.com.
- Publication Type:Journal Article
- MeSH:
Animals;
Bone Marrow;
Chitosan;
Hematopoietic Stem Cell Transplantation;
Hematopoietic System;
Mice;
Particulate Matter/toxicity*
- From:
Journal of Experimental Hematology
2021;29(5):1478-1484
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the toxic damage and possible mechanism of chronic exposure of ambient particulate matter (PM
METHODS:Mice were treated with different doses (150, 300, 600 mg/kg) of chitosan after exposure to PM
RESULTS:Compared with the mice in control group, IL-2 secretion and CXCL12 expression were decreased in the bone marrow of PM
CONCLUSION:Chronic exposure of PM
