Clinical efficiency of holmium laser enucleation of the prostate for small-volume benign prostatic hyperplasia with severe LUTS.
- Author:
Zi-Wei WEI
1
;
Meng GU
1
;
Yan-Bo CHEN
1
;
Chong LIU
1
;
Heng-Hua ZHOU
2
;
Man-Mei LONG
2
;
Yu-Cheng TAO
1
;
Xiang WAN
1
;
Qi CHEN
1
;
Zhi-Kang CAI
1
;
Zhong WANG
1
Author Information
1. Department of Urology.
2. Department of Pathology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.
- Publication Type:Journal Article
- Keywords:
clinical efficiency;
enucleation;
holmium laser;
lower urinary tract symptoms;
small-volume benign prostatic hyperplasia
- MeSH:
Humans;
Lasers, Solid-State;
Lower Urinary Tract Symptoms/surgery*;
Male;
Prostate/surgery*;
Prostatic Hyperplasia/surgery*;
Quality of Life;
Retrospective Studies
- From:
National Journal of Andrology
2021;27(9):787-792
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the safety and clinical efficiency of holmium laser enucleation of the prostate (HoLEP) in the treatment of small-volume BPH (SBPH) complicated by severe lower urinary tract symptoms (LUTS).
METHODS:We retrospectively analyzed the clinical data on 82 cases of SBPH with severe LUTS treated by HoLEP from January 2017 to December 2018. The patients were aged (65.5 ± 7.6) years, with a mean prostate volume of <40 ml, a total IPSS of 24.8 ± 4.6, a QOL score of 5.2 ± 0.8, the maximum urinary flow rate (Qmax) of (7.6 ± 3.7) ml/s, and a mean PSA level of (1.8 ± 1.4) μg/L.
RESULTS:All the operations were successfully completed, the mean operation time averaging (30.2 ± 5.0) min, enucleation time (26.7 ± 5.6) min and comminution time (3.5 ± 1.1) min, and the enucleated tissue weighing (20.3 ± 4.9) g. After surgery, the bladders were irrigated for (3.5 ± 1.9) h, with (3.0 ± 1.7) L of rinse solution, and catheterization lasted (24.8 ± 9.7) h. Histopathology revealed moderate or severe lymphocytic infiltration in 69 cases (84.1%). At 6 months after operation, significant improvement was observed in the IPSS, QOL, Qmax and PSA level compared with the baseline (P < 0.05). To date, no urethral stricture-related reoperation was ever necessitated.
CONCLUSIONS:HoLEP is safe and effective for the treatment of SBPH complicated by severe LUTS and can be employed after adequate preoperative evaluation of the patient.《.
