Research Progress in CircRNA and Radiotherapy Resistance of Non-small Cell Lung Cancer.
10.3779/j.issn.1009-3419.2021.101.37
- Author:
Weilong LI
1
;
Shenglin MA
2
;
Shirong ZHANG
3
,
4
Author Information
1. Zhejiang Chinese Medical University, Hangzhou 310053, China.
2. Hangzhou Cancer Hospital, Hangzhou 310002, China.
3. The Four School of Medicine, Zhejiang Chinese Medical University
4. Hangzhou First People's Hospital, Hangzhou 310006, China.
- Publication Type:Journal Article
- Keywords:
CircRNA;
Lung neoplasms;
Radiotherapy;
Research progress;
Resistance
- MeSH:
Carcinoma, Non-Small-Cell Lung/radiotherapy*;
Cell Proliferation;
Humans;
Lung Neoplasms/radiotherapy*;
MicroRNAs;
RNA, Circular
- From:
Chinese Journal of Lung Cancer
2021;24(11):770-776
- CountryChina
- Language:Chinese
-
Abstract:
As the main type of lung cancer, non-small cell lung cancer (NSCLC) is a common cancer which is characterized by low 5-year survival rate and worse prognosis. Nowadays, some studies show that the low survival rate and worse prognosis are due to the resistance to radiotherapy caused by circRNA. Therefore, to find out the relationship between circRNA and radiotherapy resistance of NSCLC was imoprtant. According to research the relevant literatures, the relationship between circRNA and radiotherapy resistance of NSCLC was explored. CircRNA plays an important role in the invasion, metastasis, proliferation and treatment resistance of NSCLC. The radiation resistance of tumor cells induced by circRNA has become a crucial problem in radiotherapy. CircRNA plays an important role in the radiotherapy resistance of NSCLC.
.
