Safety of Alginate-based Gastric Mucosal Protective Adhesive and Feasibility Study of Its Use as Submucosal Injection.
10.3969/j.issn.1671-7104.2021.05.016
- Author:
Muye HE
1
;
Conghui SUN
2
;
Miaomiao WANG
2
;
Mingyue QU
1
;
Chunren WANG
1
;
Han WANG
1
Author Information
1. National Institute for Food and Drug Control, Beijing, 102629.
2. Yantai university, Yantai, 264000.
- Publication Type:Journal Article
- Keywords:
alginate;
endoscopic submucosal dissection;
feasibility;
safety evaluation;
submucosal injection
- MeSH:
Adhesives;
Alginates;
Animals;
Feasibility Studies;
Gastric Mucosa;
Injections;
Rats;
Swine
- From:Chinese Journal of Medical Instrumentation
2021;45(5):546-550
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the safety of alginate based gastric mucosal protective adhesive and its feasibility as a submucosal injection.
METHODS:The feasibility of using alginate-based gastric mucosal protective gel as submucosal injection was evaluated by
RESULTS:After injection of different concentrations of alginate base mucosal protective adhesive solution, the uplift height was significantly higher than that of normal saline (
CONCLUSIONS:Gastric mucosa protector is a promising new medical device product with feasibility and good biocompatibility as submucosal uplift injection agent.
