Progress in the Treatment of Tachyarrhythmia by Pulsed Electric Field Ablation Catheter Ablation.
10.3969/j.issn.1671-7104.2021.05.010
- Author:
Zhihong ZHAO
1
;
Yonggang CHEN
2
;
Zhongping NING
1
;
Xinhua CHEN
3
Author Information
1. Department of Cardiology, Zhoupu Hospital, Shanghai University of Medical & Health Sciences, Shanghai, 201318.
2. Hangzhou Ruidi Biotechnology Co. Ltd., Hangzhou, 310003.
3. Zhejiang Medical Laboratory of Pulsed Power Technology, Hangzhou, 310003.
- Publication Type:Journal Article
- Keywords:
irreversible electroporation;
pulsed electric field ablation;
tachyarrhythmia
- MeSH:
Atrial Fibrillation/surgery*;
Catheter Ablation;
Catheters;
Humans;
Pulmonary Veins/surgery*;
Tachycardia
- From:Chinese Journal of Medical Instrumentation
2021;45(5):517-523
- CountryChina
- Language:Chinese
-
Abstract:
Pulsed electric field(PEF) provides high-energy instantaneous pulse and release energy to myocardial cell membrane, resulting in irreversible electroporation and causes myocardial cell contents leakage, destruction of intracellular homeostasis, cell death, and slight inflammatory response. PEF as non-thermal energy promotes the design and application of arrhythmia ablation catheter to enter a new stage. There are currently limited clinical studies that have proved the safety and effectieness of Farawave PEF catheter, PVAC GOLD PEF catheter, Lattice-tip Sphere-9 PEF and radiofrequency (RF) catheter used for atrial fibrillation ablation, but still need further discussion. The research of atrial fibrillation ablation with PEF is under study in China. In this paper, the design and application of PEF ablation for tachyarrhythmia are reviewed.
