Metabolic Syndrome Emerging from Menopause.
10.6118/jksm.2011.17.3.127
- Author:
Myoungseok HAN
1
Author Information
1. Department of Obstetrics and Gynecology, Dong-A University College of Medicine, Busan, Korea. hmsobgy@dau.ac.kr
- Publication Type:Review
- Keywords:
Cardiovascular disease;
Menopause;
Metabolic syndrome X
- MeSH:
Cardiovascular Diseases;
Dyslipidemias;
Estrogens;
Female;
Humans;
Insulin Resistance;
Life Style;
Lipid Metabolism;
Menopause;
Metabolic Syndrome X;
Obesity, Abdominal;
Polycystic Ovary Syndrome;
Prevalence;
Risk Factors;
Weight Gain
- From:The Journal of Korean Society of Menopause
2011;17(3):127-135
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Metabolic syndrome (MS) in women, which is characterized with central obesity, insulin resistance, and dyslipidemia, is associated with high risk of cardiovascular disease (CVD) and diabetes. Menopause may be related with the prevalence of MS and increased CVD risk through effects on central obesity, lipid metabolism, and prothrombotic state. The emergence of these risk factors may be a direct result from the failure of estrogen production. Alternatively, metabolic changes with estrogen deficiency may be the indirect cause of those risks. Additionally, most women may have a few chances of developing MS during their life, such as pregnancy-related weight gain, hormonal contraceptive use and polycystic ovary syndrome. Therefore, it is difficult to conclude that menopause itself can be the cause of MS. Representative managements of MS are life style modification and use of lipid lowering medication. This article will review the relationship between the development of MS and menopause. A better understanding on the metabolic changes with menopause will help identify women with risk factors of CVD and provide appropriate interventions
