Research progress of bone marrow edema-like lesions in knee osteoarthritis.
10.12200/j.issn.1003-0034.2021.12.018
- Author:
Hou-Jian ZHANG
1
;
Sai-Ya YE
1
;
Xiao-Jian WANG
1
;
Pei-Jian TONG
1
Author Information
1. Zhejiang Provincial Hospital of Traditional Chinese Medicine, Hangzhou 310006, Zhejiang, China.
- Publication Type:Review
- Keywords:
Bone marrow lesions;
Osteoarthritis;
Review
- MeSH:
Bone Marrow/diagnostic imaging*;
Bone Marrow Diseases/diagnostic imaging*;
Edema/diagnostic imaging*;
Humans;
Knee Joint;
Magnetic Resonance Imaging;
Osteoarthritis, Knee/diagnostic imaging*
- From:
China Journal of Orthopaedics and Traumatology
2021;34(12):1186-1190
- CountryChina
- Language:Chinese
-
Abstract:
Knee osteoarthritis-associated bone marrow edema-like lesions (KOA-BMLs) is a common MRI imaging feature, which is mainly manifested as abnormal bone marrow hyperintensity in subchondral bone on T2 imaging. The formation of KOA-BMLs may be related to the abnormality of lower limb force line and subchondral bone perfusion, and related histopathological studies showed that the remodeling of bone and bone marrow in these damaged areas was abnormally increased. In KOA patients, the size of BMLs can fluctuate or even disappear in a relatively short period of time, and was closely related to pain, subchondral bone cyst formation, and the progression of KOA. However, the current treatment methods for KOA-BMLs are limited, and there is no uniform guideline or expert consensus, mainly includingmedication, physical therapy and surgical treatment. This article reviews the research progress of the disease characteristics and treatment of KOA-BMLs in order to provide guidance for the clinical diagnosis and treatment of KOA-BMLs.
