Research progress on the effect of surface charge of biomaterials on bone formation.
10.7507/1001-5515.202104022
- Author:
Shaotai WANG
1
;
Dongsheng SONG
1
;
Chunyan QIAO
2
Author Information
1. Department of Orthodontics, Hospital of Stomatology, Jilin University, Changchun 130021, P.R.China.
2. Department of Pathology, Hospital of Stomatology, Jilin University, Changchun 130021, P.R.China.
- Publication Type:Journal Article
- Keywords:
biomaterials;
bone defects;
immune regulation;
surface charge;
surface composition;
surface wettability
- MeSH:
Biocompatible Materials;
Osteogenesis;
Regenerative Medicine;
Tissue Engineering
- From:
Journal of Biomedical Engineering
2021;38(6):1229-1234
- CountryChina
- Language:Chinese
-
Abstract:
With the continuous progress of materials science and biology, the significance of biomaterials with dual characteristics of materials science and biology is keeping on increasing. Nowadays, more and more biomaterials are being used in tissue engineering, pharmaceutical engineering and regenerative medicine. In repairing bone defects caused by trauma, tumor invasion, congenital malformation and other factors, a variety of biomaterials have emerged with different characteristics, such as surface charge, surface wettability, surface composition, immune regulation and so on, leading to significant differences in repair effects. This paper mainly discusses the influence of surface charge of biomaterials on bone formation and the methods of introducing surface charge, aiming to promote bone formation by changing the charge distribution on the surface of the biomaterials to serve the clinical treatment better.
