Correlation between internal damage due to seven emotions in traditional Chinese medicine and pathogenesis of breast cancer from perspective of psychological stress.
10.19540/j.cnki.cjcmm.20210712.601
- Author:
Xue-Mei LIU
1
;
Hui-Min LIU
1
;
Le-le MA
1
;
Ding-Kun ZHANG
1
;
Hong-Yan MA
1
;
Jun-Zhi LIN
2
;
Run-Chun XU
1
Author Information
1. State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine Chengdu 611137, China.
2. Traditional Chinese Mdeicine Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine Chengdu 610072, China.
- Publication Type:Journal Article
- Keywords:
breast cancer;
internal damage due to the seven emotions;
molecular mechanism;
psychological stress
- MeSH:
Breast Neoplasms/genetics*;
Emotions;
Female;
Humans;
Hypothalamo-Hypophyseal System;
Medicine, Chinese Traditional;
Pituitary-Adrenal System;
Stress, Psychological
- From:
China Journal of Chinese Materia Medica
2021;46(24):6377-6386
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer is a major chronic disease threatening women's health. It has topped the global cancers as the diagnosed cases outnumbered lung cancer patients in 2020. Internal damage due to the seven emotions is an important cause of breast cancer and the disorders of hypothalamic-pituitary-adrenal(HPA) axis and endocrine system and the abnormal immune defense mechanism in response to psychological stress all affect the occurrence and development of breast cancer. It is noteworthy that the theory of seven emotions in traditional Chinese medicine and the psychological stress theory of modern medicine have something in common in some aspects. Therefore, this study explored the correlation between internal damage due to the seven emotions and psychological stress and analyzed the molecular biological mechanisms of psychological stress influencing breast cancer from the perspective of modern medicine, which is helpful to reasonably prevent breast cancer and other related tumors and improve the prognosis of breast cancer patients through emotion regulation.