Advances in research on chemical composition of Picrorhiza scrophulariiflora and P. kurroa and their biological activities.
10.19540/j.cnki.cjcmm.20210708.601
- Author:
Li-Zheng MA
1
;
Li-Ping KANG
2
;
Tie-Gui NAN
2
;
Zhi-Lai ZHAN
2
;
Lan-Ping GUO
2
Author Information
1. State Key Laboratory of Dao-di Herbs Breeding Base, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China School of Traditional Chinese Medicine, Guangdong Pharmaceutical University Guangzhou 510006, China.
2. State Key Laboratory of Dao-di Herbs Breeding Base, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
- Publication Type:Review
- Keywords:
Picrorhiza kurroa;
Picrorhiza scrophulariiflora;
chemical composition;
pharmacological activities;
research advance
- MeSH:
Iridoid Glycosides;
Picrorhiza;
Triterpenes/pharmacology*
- From:
China Journal of Chinese Materia Medica
2021;46(23):6114-6129
- CountryChina
- Language:Chinese
-
Abstract:
At present, 141 compounds have been isolated from Picrorhiza scrophulariiflora and P. kurroa of the Scrophulariaceae plants, including 46 iridoid glycosides, 29 tetracyclic triterpenoids, 25 phenylpropanoids, and 11 phenylethanoid glycosides. Pharmacological studies have demonstrated that they have liver-, heart-, brain-, kidney-, and nerve cells-protecting effects as well as anti-tumor, anti-inflammatory, anti-bacterial, anti-asthma, anti-diabetic, immunomodulatory, and blood lipid-lowering activities. This article reviews the chemical components and pharmacological activities of P. scrophulariiflora and P. kurroa, aiming to provide a basis for the in-depth research, development, and utilization of the two plants.
