Health risk assessment of exogenous harmful pollutants in Chinese medicine: a review.
10.19540/j.cnki.cjcmm.20210528.605
- Author:
Ming SUI
1
;
Dan-Dan KONG
2
;
Shu-Min DING
3
;
Mei-Hua YANG
2
Author Information
1. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education,Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100193, China School of Pharmacy, Changzhou University Changzhou 213164, China.
2. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education,Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100193, China.
3. School of Pharmacy, Changzhou University Changzhou 213164, China.
- Publication Type:Review
- Keywords:
Chinese medicine;
exogenous harmful pollutants;
health risk assessment;
research progress
- MeSH:
Drug Contamination;
Drugs, Chinese Herbal/analysis*;
Environmental Pollutants/analysis*;
Humans;
Medicine, Chinese Traditional;
Pesticide Residues/analysis*;
Risk Assessment
- From:
China Journal of Chinese Materia Medica
2021;46(21):5593-5599
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the quality and safety problems have been limiting the internationalization of Chinese medicine. The pollutants in Chinese medicine, particularly the exogenous harmful pollutants mainly including mycotoxins, pesticide residues, heavy metals, harmful elements, and sulfur dioxide, are of high risks for people. Therefore, the World Health Organization(WHO) and relevant national organizations have clearly defined the maximum residue limits(MRLs) of such pollutants. Chinese Pharmacopoeia(2020 edition, volume Ⅳ) also demonstrates the detection methods, MRLs and preliminary risk assessment methods for four typical exogenous harmful pollutants in Chinese medicine. Therefore, continuous optimization of the health risk assessment system can further help further raise the quality and safety of Chinese medicine. This paper reviews the research on the health risk assessment of four typical exogenous harmful pollutants in Chinese medicine and discusses the problems of and challenges for the assessment system, which is expected to lay a scientific basis for the establishment of the risk warning mode and response measures suitable for specific types of Chinese medicine.
