Biosynthesis and metabolism regulation of terpenoids in Pogostemon cablin: a review.
10.19540/j.cnki.cjcmm.20210722.102
- Author:
Yin-Yi YAO
1
;
Meng-Ling HE
2
;
Ying-Ying LI
1
;
Jun-Hong XIA
3
;
Han-Jing YAN
2
;
Hong-Yi ZHANG
2
Author Information
1. School of Traditional Chinese Medicine, Guangdong Pharmaceutical University Guangzhou 510006, China.
2. School of Traditional Chinese Medicine, Guangdong Pharmaceutical University Guangzhou 510006, China Key Laboratory of State Administration of Traditional Chinese Medicine for Production & Development of Cantonese Medicinal Materials Guangzhou 510006, China Comprehensive Experimental Station of Guangzhou,Chinese Materia Medica, China Agriculture Research System Guangzhou 510006, China.
3. School of Life Sciences, Sun Yat-sen University Guangzhou 510275, China.
- Publication Type:Review
- Keywords:
Pogostemon cablin;
biosynthesis;
metabolism regulation;
patchouli alcohol(PA);
pogostone(PO)
- MeSH:
Pogostemon/genetics*;
Terpenes;
Transcription Factors/genetics*
- From:
China Journal of Chinese Materia Medica
2021;46(21):5560-5567
- CountryChina
- Language:Chinese
-
Abstract:
The terpenoids in Pogostemon cablin have complex structures and abundant pharmacological effects. Patchouli alcohol(PA) and pogostone(PO) have a high medicinal value by virtue of anti-tumor, anti-inflammatory, antibacterial, antioxidant, and other biological activities. Due to the low content of terpenoid metabolites in P. cablin, the study of biosynthesis and metabolism regulation can provide a biosynthetic basis for obtaining high-content terpenoids. In this study, key enzyme genes in biosynthesis, transcription factors in metabolism regulation, spatio-temporal expression of terpene synthase were reviewed, aiming to provide a reference for the development, protection, and utilization of P. cablin resources.
