Research progress of Phyllanthi Fructus and prediction of its Q-markers.
10.19540/j.cnki.cjcmm.20210810.201
- Author:
Hao-Zhou HUANG
1
;
Jing-Cai CHEN
1
;
Ding-Kun ZHANG
1
;
Meng-Qi LI
2
;
Qin-Chi XIAN
1
;
San-Hu FAN
3
;
Peng TAN
4
;
Wan-Min MAO
5
;
Feng LIN
5
;
Jun-Zhi LIN
6
;
Li HAN
1
Author Information
1. State Key Laboratory of Characteristic Chinese Drug Resources in Southwest China, School of Pharmacy, Chengdu University of Traditional Chinese Medicine Chengdu 611137, China.
2. Sichuan Nursing Vocational College Chengdu 610100, China.
3. Sanlejiang Pharmaceutical-Chengdu Traditional Chinese Medicine Joint Laboratory Chengdu 610000, China.
4. State Key Laboratory of Biological Evaluation of Traditional Chinese Medicine Quality, National Administration of Traditional Chinese Medicine,Sichuan Academy of Chinese Medicine Sciences Chengdu 610041, China.
5. Dechang Bureau of Agriculture and Rural Affairs,Liangshan Yi Autonomous Prefecture,Sichuan Province Dechang 615500, China.
6. Sichuan Key Laboratory of Traditional Chinese Medicine Regulating Metabolic Diseases, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine Chengdu 610072, China.
- Publication Type:Journal Article
- Keywords:
Phyllanthi Fructus;
gallic acid;
quality marker(Q-marker);
research progress
- MeSH:
China;
Drugs, Chinese Herbal;
Fruit;
Medicine, Tibetan Traditional;
Quality Control
- From:
China Journal of Chinese Materia Medica
2021;46(21):5533-5544
- CountryChina
- Language:Chinese
-
Abstract:
Phyllanthi Fructus, a unique Chinese and Tibetan medicinal plant with both edible and medical values, has high potential of cultivation and development. The resources of Phyllanthi Fructus in China are rich, mainly distributed in Yunnan, Sichuan, Fujian, Guangdong, Guangxi, etc. Phyllanthi Fructus is widely used in the clinical practice of Chinese medicine and plays an important role in Tibetan medicine, Uyghur medicine, Yi medicine, and Mongolian medicine. Phyllanthi Fructus mainly contains phenolic acids,tannins, terpenes, sterols, fatty acids, flavonoids, amino acids and other compounds. Modern pharmacological studies show that Phyllanthi Fructus has antioxidant, anticancer, blood lipid-lowering, liver protective, antimicrobial, anti-inflammatory, and immune regulatory activities. In this paper, the research status of Phyllanthi Fructus was reviewed from the aspects of herbal textual research,chemical composition, and pharmacological action. The quality markers(Q-markers) of Phyllanthi Fructus were predicted and analyzed from the aspects of biogenic pathway, specificity and measurability of chemical components, efficacy, properties, new clinical uses, drug-food homology, and transformation of polyphenols. The results will provide a scientific basis for the quality control, quality evaluation, and standard formulation of Phyllanthi Fructus.
