Research progress on chemical constituents and pharmacological activities of seabuckthorn and prediction of its Q-markers.
10.19540/j.cnki.cjcmm.20210520.201
- Author:
Ning-Ning WANG
1
;
Wen-Hui ZHENG
2
;
Kai-Xue ZHANG
1
;
Xiu-Feng WEN
3
;
Shun-Guang LU
3
;
Zhi-Gang YANG
1
Author Information
1. School of Pharmacy, Lanzhou University Lanzhou 730000, China.
2. Tianjin Institute of Pharmaceutical Research Co., Ltd. Tianjin 300450, China.
3. Seabuckthorn Development and Management Center, Ministry of Water Resources Beijing 100058, China.
- Publication Type:Review
- Keywords:
chemical constituent;
development and utilization;
pharmacological activity;
quality marker(Q-marker);
seabuckthorn
- MeSH:
Anti-Inflammatory Agents;
Biomarkers;
Drugs, Chinese Herbal;
Flavonoids;
Hippophae
- From:
China Journal of Chinese Materia Medica
2021;46(21):5522-5532
- CountryChina
- Language:Chinese
-
Abstract:
Seabuckthorn contains flavonoids, tannins, terpenoids, polysaccharides, and vitamins, which have anti-inflammation,anti-oxidation, liver protection, anti-cardiovascular disease, anti-aging, immune enhancing, anti-tumor, and anti-bacterial activities.We reviewed the papers focusing on the chemical constituents, pharmacological activities, and utilization of seabuckthorn. The quality markers(Q-markers) of seabuckthorn were predicted and analyzed based on original plant phylogeny, chemical composition correlation, traditional medicinal properties, pharmacodynamic correlation, traditional and extended efficacy, pharmacokinetics, metabolic processes, and measurable components. With this review, we aim to provide theoretical reference for the quality control and quality standard establishment of seabuckthorn, so as to promote the rational exploitation and utilization of seabuckthorn resources, and improve the healthy and sustainable development of seabuckthorn industry.
