Review of chemical composition, pharmacological effects, and clinical application of Salviae Miltiorrhizae Radix et Rhizoma and prediction of its Q-markers.
10.19540/j.cnki.cjcmm.20210630.203
- Author:
Xiao-Xiao SHAN
1
;
Bang-Zhen HONG
1
;
Jie LIU
1
;
Guo-Kai WANG
2
;
Wei-Dong CHEN
1
;
Nian-Jun YU
2
;
Dai-Yin PENG
2
;
Lei WANG
1
;
Cai-Yun ZHANG
1
Author Information
1. School of Pharmacy, Anhui University of Chinese Medicine Hefei 230012, China Synergetic Innovation Center of Anhui Authentic Chinese Medicine Quality Improvement Hefei 230012, China Anhui Provincial Key Laboratory of Chinese Medicinal Formula Hefei 230012, China.
2. School of Pharmacy, Anhui University of Chinese Medicine Hefei 230012, China Synergetic Innovation Center of Anhui Authentic Chinese Medicine Quality Improvement Hefei 230012, China.
- Publication Type:Review
- Keywords:
Salviae Miltiorrhizae Radix et Rhizoma;
chemical composition;
clinical application;
pharmacological effects;
quality control;
quality marker(Q-marker)
- MeSH:
Drugs, Chinese Herbal/pharmacology*;
Medicine, Chinese Traditional;
Plant Roots;
Rhizome;
Salvia miltiorrhiza
- From:
China Journal of Chinese Materia Medica
2021;46(21):5496-5511
- CountryChina
- Language:Chinese
-
Abstract:
Salviae Miltiorrhizae Radix et Rhizoma is a Chinese herbal medicine that promotes blood circulation to remove blood stasis, nourishes blood to tranquilize the mind, and cools blood to disperse carbuncles. Salviae Miltiorrhizae Radix et Rhizoma has microcirculation-improving, blood vessel-dilating, atherosclerosis-preventing, anti-inflammatory, anti-tumor, and blood pressure-and blood lipid-lowering activities. As research progresses, the chemical composition, pharmacological effect, and clinical application of Salviae Miltiorrhizae Radix et Rhizoma have attracted much attention. We reviewed the research progress in this field. Based on the concept of quality marker(Q-marker) in traditional Chinese medicine, the Q-markers of Salviae Miltiorrhizae Radix et Rhizoma were predicted and analyzed from the aspects of quality transfer, traceability, ingredient specificity, association between ingredients and pharmacological effects, ingredient predictability, and compounding environment. This review provides a scientific basis for the quality control of Salviae Miltiorrhizae Radix et Rhizoma and its preparations.
