Modern research progress of traditional Chinese medicine Paeoniae Radix Alba and prediction of its Q-markers.
10.19540/j.cnki.cjcmm.20210818.201
- Author:
Jia-Xin XU
1
;
Jun XU
2
;
Yong CAO
3
;
Yue-Jian ZHU
3
;
Xiang-Yu LI
3
;
De-Zhu GE
3
;
Lei MA
3
;
Tie-Jun ZHANG
2
;
Chang-Xiao LIU
2
Author Information
1. School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine Tianjin 300193, China.
2. Tianjin Key Laboratory of Quality Marker of Traditional Chinese Medicine, Tianjin Institute of Pharmaceutical Research Tianjin 300301, China State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research Tianjin 300301, China.
3. Anhui Jiren Pharmaceutical Co., Ltd. Bozhou 236800, China Anhui Innovation Center of Extraction Technology of Chinese Medicinal Materials Bozhou 236800, China.
- Publication Type:Journal Article
- Keywords:
Paeoniae Radix Alba;
chemical composition;
pharmacological effects;
quality evaluation;
quality markers(Q-markers
- MeSH:
Drugs, Chinese Herbal;
Medicine, Chinese Traditional;
Monoterpenes;
Paeonia;
Plant Extracts
- From:
China Journal of Chinese Materia Medica
2021;46(21):5486-5495
- CountryChina
- Language:Chinese
-
Abstract:
Paeoniae Radix Alba is the dried root of Paeonia lactiflora, which was first recorded in the Shennong's Classic of Materia Medica and listed as the top grade. It is a common blood-tonifying herb, and its chemical components are mainly monoterpenes and their glycosides, triterpenes, flavonoids and so on. Modern research has demonstrated that Paeoniae Radix Alba has the activities of anti-inflammation, pain easing, liver protection, and anti-oxidation, and thus it is widely used in clinical practice and has broad development prospects. In this paper, the research progress on the chemical composition, pharmacological effects, and quality control of Paeoniae Radix Alba were summarized. On this basis, the Q-markers of Paeoniae Radix Alba were predicted from the aspects of mass transfer and traceability, chemical composition specificity, and availability and measurability of chemical components, which will provide a scientific basis for the quality evaluation of Paeoniae Radix Alba.
