Effect of androgen on corpus cavernosal strip in the rabbit.
- Author:
Young Chan KIM
1
;
Hyung Ki CHOI
;
Young Soo AHN
;
Kyung Hwan KIM
Author Information
1. Department of Urology, Yonsei University Medicine College, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
androgen;
impotence;
rabbit;
cavernosal strip
- MeSH:
Acetylcholine;
Erectile Dysfunction;
Humans;
Male;
Relaxation;
Testosterone;
Vasoactive Intestinal Peptide
- From:Korean Journal of Urology
1992;33(4):717-721
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Testosterone is intimately related to normal sexual functioning. However most impotent patients have a normal level of circulating free testosterone. In this study. the effects of testosterone and dihyrotestosterone were observed using the isolated corpus cavernosal strip from the rabbit. Pre-treatment of testosterone and dihyrotestosterone had no effect on the contraction induced by a-adrenergic agonist. Furthermore both of them had no synergistic effect on the relaxation produced by acetylcholine or vasoactive intestinal polypeptide. Further studies about the central effect are needed for clarifying the action mechanism of androgen.
