Withania somnifera: a kind of food-medicine plant popular in world in recent years.
10.19540/j.cnki.cjcmm.20210725.101
- Author:
Yue WANG
1
;
Kai-Lin YANG
1
;
Chun-Nian HE
1
;
Pei-Gen XIAO
1
Author Information
1. Institute of Medicinal Plant Development, Chinese Academy of Medicinal Sciences & Peking Union Medicinal College Beijing 100193, China Key Laboratory of Bioactive Substances and Resources Utilisation of Chinese Herbal Medicine, Ministry of Education Beijing 100193, China.
- Publication Type:Journal Article
- Keywords:
Withania somnifera;
chemical composition;
food-medicine;
pharmacological activity;
safety evaluation
- MeSH:
Animals;
China;
Humans;
Neoplasms;
Plant Extracts;
Withania;
Withanolides
- From:
China Journal of Chinese Materia Medica
2021;46(20):5159-5165
- CountryChina
- Language:Chinese
-
Abstract:
Withania somnifera, also known as Indian ginseng, is an important traditional medicine in the Ayurvedic medical system of India, which has a significant effect of adaptation. Modern studies have shown that the main chemical components of W. somnifera are withanolides, which have antioxidant, anti-tumor, enhancing immunity, cardiovascular protection, neuroprotection, anti-stress, anti-stress reaction and hypoglycemic activities. Studies on human, animal, mutagenesis, genotoxicity, reproductive toxicity and drug interaction showed that W. somnifera had good safety. Clinical trials have proved that W. somnifera is effective in treating a variety of human diseases. As a famous traditional medicine and modern dietary supplement, it has a high reputation and market in the international health product market, but in China, there is little scientific research, market development, product introduction and application. In this paper, the traditional application, chemical composition, pharmacological activity, safety evaluation and clinical study of the plant were introduced, so as to increase the understanding of the dual use of the plant, and to provide reference for the future introduction of the product, the service to the health of the Chinese people and the promotion of the "double cycle" of the trade of health products between China and the international community.
