A novel alkaloid from Corydalis tomentella.
10.19540/j.cnki.cjcmm.20210706.201
- Author:
Xuan-Ning LONG
1
;
Feng HAN
2
;
Lin WEI
1
;
Fan-Cheng MENG
1
;
Shen-Yue QU
1
;
Min CHEN
1
Author Information
1. College of Pharmaceutical Sciences, Southwest University Chongqing 400715, China.
2. Chongqing Institute of Medical Plant Cultivation Chongqing 408435, China.
- Publication Type:Journal Article
- Keywords:
Corydalis tomentella;
alkaloid;
chemical constituent
- MeSH:
Alkaloids;
Chromatography, High Pressure Liquid;
Chromatography, Reverse-Phase;
Corydalis;
Plant Extracts
- From:
China Journal of Chinese Materia Medica
2021;46(19):5020-5026
- CountryChina
- Language:Chinese
-
Abstract:
The chemical constituents in the ethyl acetate extract of Corydalis tomentella was isolated and purified with normal and reversed phase silica gel column chromatography, Sephadex LH-20, MCI, and semi-preparative HPLC. The compound structures were identified based on spectroscopic experiments and reported papers. Finally, eighteen compounds(1-18) were obtained from C. tomentella, including 17 alkaloids and 1 terpenoid. Among them, compound 1(tomentellaine A) was a novel alkaloid. Compounds 2-5, 7-14, and 16-18 were isolated from this plant for the first time.
