Olmesartan-associated Enteropathy.
10.3881/j.issn.1000-503X.13268
- Author:
Long ZOU
1
;
Qiang WANG
1
;
Yue LI
1
;
Ai-Ming YANG
1
Author Information
1. Department of Gastroenterology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
- Publication Type:Review
- Keywords:
adverse event;
chronic diarrhea;
intestinal malabsorption;
olmesartan
- MeSH:
Angiotensin Receptor Antagonists;
Humans;
Imidazoles;
Intestinal Diseases/diagnosis*;
Tetrazoles/adverse effects*
- From:
Acta Academiae Medicinae Sinicae
2021;43(6):986-990
- CountryChina
- Language:Chinese
-
Abstract:
Olmesartan,an angiotensin Ⅱ receptor blocker,is a commonly used antihypertensive drug.Several case reports and cohort studies in recent years have described a severe gastrointestinal adverse event with chronic diarrhea,intestinal malabsorption,and weight loss after the administration of olmesartan.In such cases,the patients recovered after discontinuing olmesartan.This adverse effect is called olmesartan-associated enteropathy(OAE).This article reviews the potential pathogenesis and clinical characteristics of OAE,which broadens the disease spectrum for the differential diagnosis of chronic diarrhea and intestinal malabsorption.
