Multiple Gastrointestinal Stromal Tumor with Neurofibromatosis Type Ⅰ:Report of One Case.
10.3881/j.issn.1000-503X.13074
- Author:
Hong-Yan XU
1
;
Bo WU
1
;
Qian-Tong DONG
2
;
Sai-Zhen CHEN
1
Author Information
1. Department of Pharmaceutics,Taizhou Central Hospital(Taizhou University Hospital), Taizhou,Zhejiang 318000,China.
2. Department of Gastrointestinal Surgery,the First Affiliated Hospital of Wenzhou Medical University, Wenzhou,Zhejiang 325000,China.
- Publication Type:Journal Article
- Keywords:
gastrointestinal stromal tumors;
neurofibromatosis type Ⅰ
- MeSH:
Gastrointestinal Stromal Tumors/genetics*;
Humans;
Neurofibromatosis 1/genetics*
- From:
Acta Academiae Medicinae Sinicae
2021;43(5):840-844
- CountryChina
- Language:Chinese
-
Abstract:
Gastrointestinal stromal tumors(GISTs)in the stomach,duodenum,and rectum have low occurrence,and the coexistence GISTs in three parts with neurofibromatosis type Ⅰ(NF-Ⅰ)is even rare.This paper reports a case of GISTs with a family history of NF-Ⅰ.There were multiple nodular masses of different sizes on the patient's face,trunk,and limbs.The patient was admitted due to chest tightness for 5 days and black stools for 1 day.Enhanced CT examination of the abdomen suggested multiple space-occupying lesions in the upper abdomen with multiple small nodules under the abdominal wall,and neurofibromatosis and intestinal stromal tumor cannot be excluded.Finally,surgical pathology confirmed that the multiple tumors in the abdominal cavity were GISTs.The case was confirmed as wild-type GISTs by genetic testing,and the patient recovered well nearly one year after the operation.
