Effects of Intravitreal Injection of Anti-vascular Endothelial Growth Factor Drugs on Ocular Blood Vessels and Blood Flow in Patients with Diabetic Retinopathy.
10.3881/j.issn.1000-503X.12580
- Author:
Hui HUANG
1
;
Ling SHI
1
;
Siyu LI
1
;
Na WU
1
;
Jie RAO
1
;
Ya-Jun WU
1
;
Xiao-Rong WU
1
Author Information
1. Department of Ophthalmology,the First Affiliated Hospital of Nanchang University,Nanchang 330006,China.
- Publication Type:Journal Article
- Keywords:
anti-vascular endothelial growth factor drug;
blood flow;
blood vessel;
diabetic retinopathy
- MeSH:
Angiogenesis Inhibitors/therapeutic use*;
Diabetes Mellitus;
Diabetic Retinopathy/drug therapy*;
Humans;
Intravitreal Injections;
Macular Edema/drug therapy*;
Pharmaceutical Preparations;
Vascular Endothelial Growth Factor A;
Vascular Endothelial Growth Factors/therapeutic use*
- From:
Acta Academiae Medicinae Sinicae
2021;43(5):796-800
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic retinopathy(DR)is the major microvascular disease in diabetic patients,and it is also one of the main blinding eye diseases in the current population.The typical pathological change of DR in the eyes is vascular endothelial growth factor(VEGF)-mediated neovascularization induced by retinal ischemic stimulation.Therefore,anti-VEGF drugs have gradually become one of the mainstream methods to treat DR and DR-induced diseases such as diabetic macular edema.Recent studies have proved that anti-VEGF drugs have certain effects on ocular blood vessels and blood flow in patients with DR,while the specific mechanism has not been fully elucidated.This article summarizes the research progress on the effects of intravitreal injection of anti-VEGF drugs on the ocular blood vessels and blood flow in patients with DR.
