Preparation and application of decellularized extracellular matrix bioink: a review.

Author: Jianing YAN ¹ ; Yi XU ¹
Author Information

1. School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.
Publication Type:Review
Keywords: 3D bioprinting; bioink; decellularized extracellular matrix; tissue engineering
MeSH: Bioprinting; Extracellular Matrix; Printing, Three-Dimensional; Tissue Engineering; Tissue Scaffolds
From: Chinese Journal of Biotechnology 2021;37(11):4024-4035
CountryChina
Language:Chinese
Abstract: Decellularized extracellular matrix (dECM), which contains many proteins and growth factors, can provide three-dimensional scaffolds for cells and regulate cell regeneration. 3D bioprinting can print the combination of dECM and autologous cells layer by layer to construct the tissue structure of carrier cells. In this paper, the preparation methods of tissue and organ dECM bioink from different sources, including decellularization, crosslinking, and the application of dECM bioink in bioprinting are reviewed, with future applications prospected.