Advances in fecal microbiota transplantation for treatment of Parkinson's disease.

Author: Minna ZHANG ¹ ; Honggang WANG ¹ ; Liujun XUE ² ; Xiaozhong YANG ¹
Author Information

1. Department of Gastroenterology, the Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Huai'an 223300, Jiangsu, China.
2. Department of Neurology, the Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Huai'an 223300, Jiangsu, China.
Publication Type:Review
Keywords: Parkinson’s disease; fecal microbiota transplantation; gut microbiota; gut-brain axis; therapy
MeSH: Aged; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Humans; Middle Aged; Neurodegenerative Diseases; Parkinson Disease/therapy*
From: Chinese Journal of Biotechnology 2021;37(11):3812-3819
CountryChina
Language:Chinese
Abstract: Parkinson's disease (PD) is a common neurodegenerative disease in middle-aged and elderly people. Patients with PD often suffer from gastrointestinal symptoms in the early stage of the disease. Several studies have confirmed that gut microbiota is involved in the progress of PD. As one of the most effective ways to reconstruct the gut microbiota, fecal microbiota transplantation (FMT) has shown potential therapeutic effects on PD. This review summarizes the basic and clinical studies of FMT in the treatment of PD.