Microbe-gut-brain axis and neurological disorders: a review.

Author: Xin SHEN ¹ ; Zhihong SUN ¹
Author Information

1. Inner Mongolia Key Laboratory of Dairy Biotechnology and Engineering, Key Laboratory of Dairy Products Processing, Ministry of Agriculture and Rural Affairs, Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Publication Type:Review
Keywords: fecal bacteria transplantation; gut-brain axis; intestinal microbes; neurological disorders; probiotic/prebiotic therapy
MeSH: Brain; Environment; Gastrointestinal Microbiome; Humans; Neurodegenerative Diseases
From: Chinese Journal of Biotechnology 2021;37(11):3781-3788
CountryChina
Language:Chinese
Abstract: Intestinal microbes have an adjuvant therapeutic effect on neurological disorders (such as Parkinson's, depression, and Alzheimer's disease). It affects brain function and host behavior through the neural pathways, the immune pathways and the microbial metabolites, the so-called gut-brain axis. This article summarizes the recent advances in the role of the microbe-gut-brain axis in neurological disorders, in order to provide new ideas for the treatment of neurodegenerative diseases.